Wednesday, March 13, 2013

Jude Law Joins Jane Got a Gun

joel edgerton jude law jane got a gun

The production of Jane Got a Gun, a Western led by?Natalie Portman, has been delayed several times.? It was finally scheduled to begin shooting next week, but a last-minute casting swap will push production back to April.? Michael Fassbender?was set to play the male lead, but his?X-Men: Days of Future Past?schedule creates a conflict that will pull him off the project.? Normally, that would be terrible news, but director?Lynne Ramsay (We Need to Talk About Kevin) has a mighty fine backup plan.? THR reports Joel Edgerton, who was looking to play the villain, will switch sides to assume Fassbender?s role.? Jude Law will come on board to play the villain and round out the lead cast.? If you can get two out of three with Fassbender, Edgerton, and Law, you win.

Scott Steindorff (The Lincoln Lawyer), Aleen Keshishian (Our Idiot Brother), and Terry Dougas (The Box) are producing.? The script by Brian Duffield follows good girl Jane (Portman), who runs away from her outlaw husband (Law) and teams up with on old flame (Edgerton) to protect her family.? Read the full synopsis for Jane Got a Gun after the break.

Here is the AFM synopsis:

natalie-portman jane got a gun

Young and pretty with a soul of pure steel, Jane Hammond (Natalie Portman) is a good girl married to one of the worst baddies in town.? When her husband Bill (Jude Law) turns against his own gang, the vicious Bishop Boys, and returns home barely alive with eight bullets in his back, Jane knows it?s time to ditch the dress for a pair of pants and strap on her own gun.? As the relentless leader John Bishop gears up for revenge, Jane?s best hope for her family?s survival rests with her old love Dan Frost (Joel Edgerton) ? a gunslinger whose hatred for Bill is only slightly overshadowed by his love for Jane.? Together Jane and Dan spring clever traps, luring Bishop?s men to certain death just as their old feelings for each other resurface amidst the flying bullets.

With director Lynne Ramsay (WE NEED TO TALK ABOUT KEVIN, MORVERN CALLAR) at the helm, the rich dimensions of these characters find their best ally with Jane out in front, taking her fate into her own hands with the kind of bravado legends are made of.

Source: http://www.rottentomatoes.com/m/1927004/news/1927004/

Bram Stoker books Paula Broadwell Photos Veterans Day 2012 Nate Silver stock market stock market Obama Acceptance Speech 2012

Tuesday, March 12, 2013

No. 3 Duke hammers North Carolina 69-53

Duke's Seth Curry (30) reacts following a basket against North Carolina during the first half of an NCAA college basketball game in Chapel Hill, N.C., Saturday, March 9, 2013. (AP Photo/Gerry Broome)

Duke's Seth Curry (30) reacts following a basket against North Carolina during the first half of an NCAA college basketball game in Chapel Hill, N.C., Saturday, March 9, 2013. (AP Photo/Gerry Broome)

North Carolina's Reggie Bullock, right, guards Duke's Ryan Kelly (34) during the first half of an NCAA college basketball game in Chapel Hill, N.C., Saturday, March 9, 2013. (AP Photo/Gerry Broome)

North Carolina's P.J. Hairston (15) drives to the basket with Reggie Bullock (35) against Duke's Seth Curry (30) during the first half of an NCAA college basketball game in Chapel Hill, N.C., Saturday, March 9, 2013. (AP Photo/Gerry Broome)

North Carolina's Desmond Hubert (14) shoots as Duke's Josh Hairston (15) defends during the first half of an NCAA college basketball game in Chapel Hill, N.C., Saturday, March 9, 2013. (AP Photo/Gerry Broome)

Duke's Seth Curry (30) reacts following a basket against North Carolina during the first half of an NCAA college basketball game in Chapel Hill, N.C., Saturday, March 9, 2013. (AP Photo/Gerry Broome)

(AP) ? Seth Curry kept burying shots against helpless North Carolina defenders to give No. 3 Duke a big lead, then Mason Plumlee dominated inside to keep the Blue Devils in complete control against their fiercest rival.

This performance was about more than just beating up the Tar Heels. It was the Blue Devils showing they're determined to play their best in March.

Curry hit his first seven shots during Duke's torrid start, helping the Blue Devils cruise to a 69-53 victory Saturday night in a game that was never in doubt.

Curry finished with 20 points, while Plumlee had his best performance in a month with 23 points and 13 rebounds. That duo provided Duke (27-4, 14-4 Atlantic Coast Conference) all the punch it needed to earn a season sweep of the Tar Heels.

"You want to be playing at your best going into the tournament and you can't afford a loss at this point in the season where you're questioning your lineups and what your identity is," Plumlee said. "It was the kind of win we needed going into tournament time."

Duke scored the game's first 14 points, never let UNC (22-9, 12-6) closer than nine and led by 25 points after halftime. The Blue Devils shot 55 percent, including 18 for 26 (69 percent) in a first half that silenced a once-rowdy Smith Center crowd and overwhelmed the once-surging Tar Heels.

If Saturday night was any indication, Duke is ready for next week's ACC tournament in Greensboro and beyond.

Curry and the Blue Devils came out with a shooting display that ran North Carolina right out of the Dean Dome by halftime. Not to mention it turned the latest renewal of the famed rivalry into a colossal dud.

Curry made one 3, hit a scooping layup and banked in a runner during Duke's 6-for-6 start that helped the Blue Devils to a football-esque 14-0 lead.

At one point, he even hit one as he fell backward to the floor, the kind of play that eliminates any doubt about whose night it's going to be.

"Guys set screens for me and I was able to create some space to get shots off, keep the defense off balance, and I was feeling good to start the game," Curry said. "I wanted to come in and set the tone for my team that we could win in this environment."

After Curry made his seventh straight shot, UNC coach Roy Williams practically wandered out near midcourt to shout at his players as they ran down on offense.

"He just toyed with us," Williams said. "He was in complete control on the offensive end."

Curry finished 8 for 13 and Plumlee took over inside by making 10 of 15 shots against the Tar Heels' undersized frontline.

"Seth's performance in the first half, he just the best player on the court," coach Mike Krzyzewski said. "In the second half, we had the best player on the court in Mason."

In each of the past two seasons, Duke had won the first meeting only to have UNC win the second to clinch the ACC regular-season title.

That story line was off the table this time. Miami took care of that by beating Clemson for the outright title earlier Saturday. Duke ? which is integrating senior Ryan Kelly back into the lineup after a two-month absence due to a foot injury ? had already clinched the No. 2 seed for the ACC tournament. North Carolina State's loss at Florida State meant the Tar Heels would be the No. 3 seed but could still tie Duke for second in the standings.

Instead, it turned into a reversal of last year's finale at Cameron Indoor Stadium, where the Tar Heels jumped all over the Blue Devils early in a blowout win.

It was the first "Senior Night" loss for Williams as a head coach, both at Kansas and at North Carolina.

UNC had gone 6-1 since going to a four-guard lineup in that first meeting, but the Tar Heels looked rattled once the Blue Devils charged in front and never recovered.

"I wasn't concerned about the score, but I was really concerned about the look on our face," Williams said. "I felt like every shot we took we were hesitant or tight ... but I didn't like the way we looked on every shot we took. We never got out of that hole."

James Michael McAdoo finished with 15 points to lead the Tar Heels despite playing with a bulging disk in his back, but the rest of his teammates did little to help him. The Tar Heels all too often settled for jumpers and didn't seem interested in attacking the rim on the way to shooting just 34 percent.

That included missing their first 11 3-point tries and finishing 1 for 14 from behind the arc, an area where they had thrived since Williams inserted 6-foot-5 sophomore P.J. Hairston into the starting lineup at the 4-spot.

Hairston finished with 14 points on 4-for-12 shooting and hit the Tar Heels' only 3 to cut the deficit to 63-49 at the 5-minute mark. But Quinn Cook answered with two driving baskets, the second a hanging shot that dropped through as the shot clock expired and took back any fleeting momentum North Carolina had built.

Cook scored 12 and completely outplayed UNC freshman point guard Marcus Paige, who regressed from his recent strong play with four points on 1-for-6 shooting and five turnovers.

"We did keep fighting, and we never gave in," Hairston said. "We still played offense and still tried to make shots, and we still tried to do different things on the defensive end to slow them down. They were just making everything they put up."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-03-10-BKC-T25-Duke-North-Carolina/id-49003b5d7d934a0d95140b85521b9307

Sarah Jones chicago marathon Johnny Depp Dead college football rankings Steel Magnolias Niels Bohr the Rumble 2012

Monday, March 11, 2013

rotherham business news: News: CBRE to look after JESSICA

Leading commercial property and real estate services adviser,?CBRE has been appointed to run an innovative ?23m infrastructure and property fund for South Yorkshire.

The Sheffield City Region Local Enterprise Partnership (LEP) has been working with Creative Sheffield, part of Sheffield City Council to create a JESSICA fund, a financial engineering mechanism used to create a revolving fund that could be used for regeneration projects such as the creation of new commercial floorspace, brownfield redevelopment or investment in infrastructure.

It uses ?8m of the government's Growing Places Fund for Sheffield City Region to leverage a further ?15m of funding from the European Regional Development Fund.

James Newman, Chairman of the Sheffield City Region LEP, said: "We have been working very closely with our private sector colleagues in the construction industry and time and time again they refer to access to finance being a major barrier to development.

"This fund is a direct response to this barrier and whilst it will not solve every problem or be suitable for every development, it puts in place a significant financial tool to help stimulate the local economy.

"Importantly, we expect to see a return on the investments, which will then be recycled into further projects over the next ten years. It is hoped that over time it will be able to also support investment across the wider city region."

Businesses wishing to find out more about how they can take advantage of the fund should attend RiDO's Property Forum on March 19 at the Holiday Inn Express, Manvers, to hear from Will Church of CBRE.

As part of the government's City Deal with Sheffield, a Sheffield city region investment fund for strategic infrastructure investment (SCRIF) is also being created that brings together different funding streams to maximise economic growth across the city region. It has the potential to provide up to ?700m over the next ten years

The South Yorkshire Transport Executive, (SYPTE) has submitted four schemes for assessment including bids to secure funding for improved public transport provision to the Waverley development and for highway and public transport improvements to ease existing problems and open up development sites at Parkgate.

CBRE website
RiDO website

Source: http://www.rothbiz.co.uk/2013/03/news-3219-cbre-to-look-after-jessica.html

bowl games rose bowl jenny mccarthy auld lang syne dick clark Happy new year fiscal cliff

New anti-clotting drug more effective than current treatment, study suggests

Mar. 10, 2013 ? Cangrelor, a novel intravenous anti-clotting medication, proves better across a broad population of patients receiving coronary stent procedures.

A new and experimental anti-clotting drug, cangrelor, proved better than the commonly used clopidogrel and was significantly more effective at preventing blood clots in a large trial of patients who underwent coronary stent procedures. These data, from the phase III CHAMPION PHOENIX study, were presented at the American College of Cardiology's 62nd Annual Scientific Session and published simultaneously in the New England Journal of Medicine.

Researchers report that the new drug, which is administered intravenously, reduced the odds of complications from stenting procedures. Specifically, those who received cangrelor had a lower combined incidence of death, myocardial infarction, ischemia-driven revascularization, or stent thrombosis at 48 hours after randomization.

"We are very excited about the potential for this new medication to reduce complications in patients receiving coronary stents for a wide variety of indications. In addition to being much quicker to take effect and more potent than currently available treatment options, this intravenous drug is reversible and has a fast offset of action, which could be an advantage if emergency surgery is needed." said Deepak L. Bhatt, MD, MPH, lead author of the study, director of the Integrated Interventional Cardiovascular Program at Brigham and Women's Hospital (BWH) and chief of cardiology at VA Boston Healthcare System, as well as professor of medicine at Harvard Medical School.

In this randomized double-blind trial, researchers compared the novel IV drug cangrelor against the oral clopidogrel standard of care in approximately 11,000 patients at 153 centers around the world. The study included a wide selection of patients with different types of heart attack, angina, and other conditions for which people undergo percutaneous coronary intervention (PCI), as long as they did not have high risk for bleeding or recent exposure to other anti-clotting drugs.

Researchers report significantly better performance by cangrelor compared with clopidogrel:

  • A 22 percent reduction in the odds of death, myocardial infarction, ischemia-driven revascularization, or stent thrombosis at 48 hours after randomization: 4.7 percent vs. 5.9 percent
  • A 38 percent reduction in the odds of stent thrombosis at 48 hours: 0.8 percent vs. 1.4 percent
  • Both treatment arms showed a quite low, statistically comparable incidence in severe bleeding at 48 hours: 0.16 percent vs. 0.11 percent.

Coronary artery stents are used in the majority of patients who undergo percutaneous coronary intervention (PCI), a common medical procedure used to treat arteries in the heart that have become narrowed or blocked due to coronary artery disease, which affects an estimated 14 million Americans. During this procedure, patients are regularly given oral doses of an anti-clotting agent to prevent blood clotting. Both cangrelor and clopidogrel interfere with the P2Y12 receptor, a platelet-surface protein that helps regulate blood clotting.

"We are encouraged by these compelling results, especially as it relates to the safety data, and believe that this drug has the potential to offer dramatic benefits to our patients" said Robert A. Harrington, M.D., chairman of medicine at Stanford University School of Medicine and co-chair of the study.

The company plans to file for approval with the Food and Drug Administration using data from CHAMPION PHOENIX and the earlier BRIDGE trial.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Brigham and Women's Hospital.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Deepak L. Bhatt, Gregg W. Stone, Kenneth W. Mahaffey, C. Michael Gibson, P. Gabriel Steg, Christian W. Hamm, Matthew J. Price, Sergio Leonardi, Dianne Gallup, Ezio Bramucci, Peter W. Radke, Petr Widimsk?, Frantisek Tousek, Jeffrey Tauth, Douglas Spriggs, Brent T. McLaurin, Dominick J. Angiolillo, Philippe G?n?reux, Tiepu Liu, Jayne Prats, Meredith Todd, Simona Skerjanec, Harvey D. White, Robert A. Harrington. Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events. New England Journal of Medicine, 2013; : 130310091208003 DOI: 10.1056/NEJMoa1300815

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/heart_disease/~3/qutnxvX2dZk/130311101823.htm

jason varitek andrew breitbart dead sheriff joe arpaio limbaugh aaron smith wilt chamberlain joe arpaio

Friday, March 8, 2013

Calif. exotic animal park lion kills Wash. intern

This Oct. 12, 2012 photo released by JP Marketing shows a 4-year-old male African lion named Couscous at Cat Haven, a private wild animal park in Dunlap, Calif. Authorities say the lion killed a female intern-volunteer on Wednesday, March 6, 2013, at Cat Haven, where the cat had been raised since it was a cub. The intern was attacked and fatally injured after getting into an enclosure with the lion, Fresno County sheriff's Sgt. Greg Collins said. (AP Photo/JP Marketing, Vicken Massoyan)

This Oct. 12, 2012 photo released by JP Marketing shows a 4-year-old male African lion named Couscous at Cat Haven, a private wild animal park in Dunlap, Calif. Authorities say the lion killed a female intern-volunteer on Wednesday, March 6, 2013, at Cat Haven, where the cat had been raised since it was a cub. The intern was attacked and fatally injured after getting into an enclosure with the lion, Fresno County sheriff's Sgt. Greg Collins said. (AP Photo/JP Marketing, Vicken Massoyan)

This 2012 photo provided by the KFSN-TV shows a 4-year-old male African lion named Couscous at Cat Haven, a private wild animal park in Dunlap, Calif. Authorities say the lion killed a female intern-volunteer on Wednesday, March 6, 2013, at Cat Haven, where the cat had been raised since it was a cub. The intern was attacked and fatally injured after getting into an enclosure with the lion, Fresno County sheriff's Sgt. Greg Collins said. (AP Photo/KFSN-TV) OUT KGPE, KSEE, KMPH, KFTV; FRESNO BEE OUT, VISALIA TIMES-DELTA OUT

This 2012 photo provided by KFSN-TV shows a 4-year-old male African lion named Couscous at Cat Haven, a private wild animal park in Dunlap, Calif. Authorities say the lion killed a female intern-volunteer on Wednesday, March 6, 2013, at Cat Haven, where the cat had been raised since it was a cub. The intern was attacked and fatally injured after getting into an enclosure with the lion, Fresno County sheriff's Sgt. Greg Collins said. (AP Photo/KFSN-TV) OUT KGPE, KSEE, KMPH, KFTV; FRESNO BEE OUT, VISALIA TIMES-DELTA OUT

An officer guards the gate near at the entrance of Cat Haven, the exotic animal park in central California where a 26-year old female volunteer intern was killed by a lion, Wednesday, March 6, 2013 in Dunlap, Calif. (AP Photo/Gosia Wozniacka)

This Wednesday, March 6, 2013 photo shows a sign posted near the gate near at the entrance of Cat Haven, the exotic animal park in central California where a 26-year old female volunteer intern was killed by a lion, in Dunlap, Calif. (AP Photo/Gosia Wozniacka)

(AP) ? The Seattle-area intern fatally mauled by a lion at a Central California exotic animal park loved lions and tigers since childhood, "was absolutely fearless" around them and hoped to work at a zoo after her six-month internship, her father said late Wednesday.

"She was at ease with those big cats," Paul Hanson, a Seattle-area attorney, said of his daughter, Dianna Hanson, 24. "They liked her."

Hanson told The Associated Press that he dropped his daughter off Jan. 2 at Cat Haven, about 45 miles east of Fresno.

"It was just a dream job for her," he said, adding that she gave him a little tour and showed him the lion Cous Cous, which authorities said killed her.

Hanson said his daughter had worked with big cats before but told him she would not be allowed to go in the lion cage.

On Wednesday, deputies found the woman severely injured and still lying inside the male African lion's enclosure with the lion nearby, said Fresno County sheriff's Lt. Bob Miller. Another park worker couldn't lure the lion into another pen, so deputies shot and killed it to safely reach the wounded woman, but she died at the scene, he said.

Cat Haven founder and executive director Dale Anderson cried as he read a one-sentence statement about the fatal mauling at the private zoo he has operated since 1993.

Investigators were trying to determine why the intern was inside the enclosure and what might have provoked the attack, sheriff's Sgt. Greg Collins said. The facility is normally closed on Wednesdays, and only one other worker was there when the mauling happened, he said.

Authorities are not pursuing a criminal investigation because all leads indicate Hanson's death was the result of an accident, sheriff's Lt. Robert Miller said Thursday.

California Department of Fish and Wildlife spokeswoman Janice Mackey said she was unaware if any state regulations would prohibit an employee from entering an exotic animal's enclosure.

The lion, Cous Cous, a 4-year-old male, had been raised at Cat Haven since it was a cub, said Tanya Osegueda, a spokeswoman for Project Survival, the nonprofit that operates the animal park.

Since the 100-acre facility just west of Kings Canyon National Park opened two decades ago, it has housed numerous big cats, including tigers, leopards and other exotic species. It is permitted to house exotic animals by the California Department of Fish and Wildlife and is regulated as a zoo by the U.S. Department of Agriculture.

Results of the last 13 USDA inspections show no violations dating back to March 2010. The most recent inspection was Feb. 4.

Despite state regulations requiring annual inspections, the California Department of Fish and Wildlife most recently inspected the facility in January 2011, when the inspector found it in "good condition" after checking animal health and features such as enclosures.

"We have to do the best we can with the resources we're provided," said department spokeswoman Jordan Traverso. "Regardless of whether it was inspected, that wouldn't have prevented this from happening."

Cat Haven's current "restricted species" permit, which expires in November, states the park was authorized to house 47 animals but had only 28. The animals must be used for scientific or educational purposes.

Actress Tippi Hedren, who founded the Shambala Preserve in Southern California, home to 53 seized or abandoned exotic pets, expressed dismay over the killing of the lion.

"It wasn't the lion's fault. It's the human's fault always," Hedren said.

Nicole Paquette, vice president of the Humane Society of the United States, said the victim of Wednesday's attack should never have been in the enclosure with the animal.

"These are big cats that are extremely dangerous, and they placed a volunteer in the actual cage with a wild animal," she said. "That should have never happened."

Officials at another big cat sanctuary, Big Cat Rescue in Tampa, Fla., told The Associated Press last year that at least 21 people, including five children, have been killed and 246 mauled by exotic cats in the United States since 1990. Over that period, 254 cats escaped and 143 were killed.

In 2007, a tiger at the San Francisco Zoo was killed by police after jumping out of its enclosure and fatally mauling a 17-year-old boy and injuring two other people.

Cat Haven has housed Bengal tigers, jaguars and leopards as well as bobcats native to the area. The facility's website says it promotes conservation and preservation of wild cats in their native habitats and offers visitors tours and educational outreach.

Anderson said Project Survival would investigate to see if the intern and the other worker on-site followed the group's protocols.

"We take every precaution to ensure the safety of our staff, animals and guests," he said in a statement.

Paul Hanson said his daughter graduated from Mountlake Terrace High School and was a 2011 graduate of Western Washington University in Bellingham, Wash., where she majored in biology.

From her early childhood, "she had a thing for lions and tigers, especially tigers," he recalled.

During college, she worked at what Hanson described as "a sizeable estate" outside Bellingham that was home to exotic animals, including three tigers and a lion. It was there she learned to care for the cats, he said.

___

Associated Press writers Kathy McCarthy in Seattle, Garance Burke in San Francisco and Sue Manning in Los Angeles contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-03-07-US-Fatal-Lion-Attack/id-ec5258be58954a728666228c007f7df0

cold mountain valentines day ideas the villages florida egoraptor gisele bundchen turbotax the bourne legacy